4-hour Live MOUD Training - 08/01/2026-Presentation Slides - 4-hour Live MOUD Training with Dr. Wyatt

Presentation Slides - 4-hour Live MOUD Training with Dr. Wyatt

Pdf Summary

This 4-hour PCSS-MOUD training, led by Stephen A. Wyatt, D.O., focused on evidence-based treatment of opioid use disorder (OUD) and broader substance use disorders (SUDs). It emphasized that addiction is a chronic brain disease shaped by genetics, environment, trauma, and social factors, and that untreated SUDs contribute substantially to mortality, healthcare use, stigma, and societal costs.<br /><br />The core of the course reviewed medications for opioid use disorder (MOUD): methadone, buprenorphine, and naltrexone. It explained their pharmacology, comparative effectiveness, safety, dosing, and treatment roles. Buprenorphine was highlighted as a partial agonist with a strong safety profile, useful for initiation, maintenance, and withdrawal management. Methadone was presented as effective but requiring more monitoring, especially for respiratory depression and QTc prolongation. Naltrexone was described as an opioid antagonist best suited for patients who can complete detoxification and prefer non-opioid treatment, though adherence and initiation can be challenging.<br /><br />The training also covered current legal and regulatory updates, including changes to DATA 2000 and DEA requirements, and discussed how to reduce barriers to care through training, low-threshold access, and stigma reduction. Patient evaluation was addressed in detail, including building therapeutic alliance, screening for co-occurring psychiatric disorders, using urine drug testing, and assessing readiness for office-based opioid treatment.<br /><br />Special topics included managing pain in patients on MOUD, treating OUD in pregnancy and adolescents, and considerations for patients with HIV, renal failure, or liver disease. The presentation stressed that MOUD improves retention in treatment, reduces illicit opioid use, decreases overdose risk, and should be continued long term when beneficial. Several case studies illustrated practical clinical decision-making around initiation, adherence, relapse risk, and treatment engagement.

Keywords

opioid use disorder

medications for opioid use disorder

buprenorphine

methadone

naltrexone

substance use disorders

addiction treatment

stigma reduction

pregnancy and adolescents

evidence-based care